General Western Blot Reagents
Abcam 4-O x o-2-nonenal (4-ONE), TRPA1 activator, 5MG
MW 154.21 g/mol, Purity >98%. Lipid peroxidation product, actively modifies histidine and lysine residues on proteins and causes protein cross-linking. Shows a variety of biological activities and is a TRPA1 activator (EC₅₀ = 1.9 μM). Active in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam D-erythro-Dihydrosphingosine-1-phosphate, sphingosine 1-phosphate receptor ligand, 5MG
MW 381.5 Da, Purity >98%. Sphingosine 1-phosphate (S1P) receptor ligand (Ki = 15 nM). May be used as negative control for intracellular effects of S1P (ab141748). Anti-fibrotic effect in fibroblasts.
The product is subject to the following: Abcam Restricted Use Statement
Abcam (±)-Bisoprolol hemifumarate, beta1 antagonist, 50MG
MW 383.48 g/mol, Purity >99%. Selective β₁ antagonist (Ki = 22.4 nM). Antihypertensive agent.
The product is subject to the following: Abcam Restricted Use Statement
Abcam SR 59230A hydrochloride, beta3 adrenoceptor antagonist, 50MG
MW 361.9 Da, Purity >99%. Potent, selective β3 adrenoceptor antagonist (IC50 values are 40, 408 and 648 nM for β3, β1 and β2, respectively). Orally active *in vivo*.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Polygodial, TRPA1 agonist, 25MG
MW 234.33 Da, Purity >97%. Selective TRPA1 agonist (EC₅₀ = 400 nM). Antinociceptive in vivo. Inhibits mitochondrial ATPase (IC₅₀ = 15 μM). Antifungal.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Cholesterol, water-permeable lipid, 25G
MW 386.7 Da, Purity >98%. Water-permeable lipid and major component of all biological membranes. Distributed in body tissues, especially the brain and spinal cord. Inhibits basal channel activity in the brain. Use as emulsifying agent and liposome preparations. Active in vivo and in vitro.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Ivermectin, Positive allosteric modulator of alpha7 nicotinic acetylcholine receptors, 50MG
MW 875.1 Da, Purity >96%. Positive allosteric modulator of α7 neuronal nicotinic acetylcholine receptor. Allosteric effector of P2X₄ receptors. Antihelmintic. Modulates glutamate- and GABA-activated chloride channels. Potentiates glycine-gated currents at low concentrations (30 nM).
The product is subject to the following: Abcam Restricted Use Statement
Abcam Clozapine, Atypical antipsychotic, 50MG
MW 326.8 Da, Purity >98%. Atypical antipsychotic compound. Broad range of actions including antagonism at D₄, D₂, 5-HT₂A, 5-HT₂C, 5-HT₃, 5-HT₆, and 5-HT₇ receptors. Also agonist at muscarinic receptors.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Tamo x ifen citrate, Estrogen receptor antagonist and partial agonist, 1G
MW 563.65 g/mol, Purity >99%. Competitive estrogen receptor antagonist and partial agonist. Inhibits estrogen dependent gene transcription and tumor growth. Additionally decreases cardiac infarction and inhibits Kir2.1, Kir2.2 and Kir2.3 potassium channels (IC₅₀ values are 0.93, 0.87 and 0.31 μM, respectively).
The product is subject to the following: Abcam Restricted Use Statement
Abcam Olanzapine, 5-HT, dopamine, histamine and muscarinic antagonist, 10MG
MW 312.43 g/mol, Purity >99%. 5-HT and D₂ antagonist (Ki values are 4 (5-HT₂A), 11 (5-HT₂C) and 57 (5-HT₃), 31 (D₁), 11 (D₂) and 27 nM (D₄)). Additionally, displays activity at: M₁, M₂, M₃, M₄, H₁, α₁ and α₂ receptors (Ki are 1.9 at (M₁), 18 (M₂), 25 (M₃), 13 (M₄), 19 (α₁) and 7 nM (α₂)). Atypical antipsychotic. Displays anxiolytic activity.
The product is subject to the following: Abcam Restricted Use Statement
![Abcam Anti-CD80 antibody [RM1104] - BSA and Azide free.](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502703749.JPG-250.jpg)
Abcam Anti-CD80 antibody [RM1104] - BSA and Azide free.
Anti-CD80 antibody [RM1104] - BSA and Azide free.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Mouse VCP peptide, 50UG
Mouse VCP peptide is a Synthetic blocking peptide. >90% purity and suitable for Neut, BL.
Protein/ Peptide/ Enzyme Synonyms: Transitional endoplasmic reticulum ATPase, TER ATPase, 15S Mg(2+)-ATPase p97 subunit, Valosin-containing protein, VCP
Conjugation: Unconjugated
The product is subject to the following: Abcam Restricted Use Statement
Abcam D-(+)-Galactose, C-4 epimer of glucose, 25G
MW 180.16 g/mol, Purity >98%. C-4 epimer of glucose. Aldohexose that serves as an energy source and as an essential component of glycolipids and glycoproteins.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Bisindolylmaleimide x I hydrochloride, PKC inhibitor, 5MG
MW 489 Da, Purity >98%. Selective, cell-permeable protein kinase C (PKC) inhibitor that displays 10-fold greater selectivity for PKCα (IC₅₀ = 9 nM) and 4-fold greater selectivity for PKCβI (IC₅₀ = 28 nM) over Ca²+-independent PKCε (IC₅₀ = 108 nM). Enhances cardiac contractility and protection from heart failure. Prevents T-cell activation and proliferation (IC₅₀s ranging from 30-150 nM) associated with chronic inflammatory responses in vivo. Also inhibits GRK2, GRK5, and GRK6 (IC₅₀ values are 29, 3.6, and 16 μM, respectively).
The product is subject to the following: Abcam Restricted Use Statement
Abcam AMQI (7-Aceto x y-1-methylquinolinium iodide), Fluorogenic cholinesterase substrate, 1G
MW 329.13 Da, Purity >98%. Fluorogenic cholinesterase substrate. Hydrolyses to highly fluorescent 7-hydroxy-1-methyl quinolinium iodide.
The product is subject to the following: Abcam Restricted Use Statement